A fully integrated biomimetic microfluidic device for evaluation of sperm response to thermotaxis and chemotaxis-Reference-Cited by-同舟云学术

A fully integrated biomimetic microfluidic device for evaluation of sperm response to thermotaxis and chemotaxis

Published:2021 Issue:2 Volume:21 Page:310-318
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Yan Yimo¹²³⁴⁵,Zhang Boxuan¹²³⁴⁵,Fu Qiqi¹²³⁴⁵,Wu Jian⁶³⁷⁸,Liu Ran¹²³⁴⁵

Affiliation:

1. Department of Biomedical Engineering

2. School of Medicine

3. Tsinghua University

4. Beijing

5. 100084 China

6. Tsinghua Shenzhen International Graduate School

7. Shenzhen

8. China

Abstract

We developed a fully integrated biomimetic microfluidic system for screening sperm for their characteristics when exposed to temperature and chemical gradients.

Funder

National Key Research and Development Program of China

Tsinghua University

National Natural Science Foundation of China

Guangdong Science and Technology Department

Shenzhen Knowledge Innovation Program

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/LC/D0LC00845A

Reference44 articles.

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2. M. J. Harper , Germ Cells and Fertilization , 1982 , vol. 1 , pp. 102–127

3. Sperm transport in the female reproductive tract

4. Sperm capacitation in humans is transient and correlates with chemotactic responsiveness to follicular factors.

5. Sperm guidance in mammals — an unpaved road to the egg

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