Ganoderic acid improves 5-fluorouracil-induced cognitive dysfunction in mice-Reference-Cited by-同舟云学术

Ganoderic acid improves 5-fluorouracil-induced cognitive dysfunction in mice

Published:2021 Issue:24 Volume:12 Page:12325-12337
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Abulizi Abudumijiti¹^ORCID,Ran Jianhua²,Ye Yuwei¹,An Yongpan¹,Zhang Yukun¹,Huang Zhizhen¹^ORCID,Lin Simei¹,Zhou Hong¹,Lin Dongmei³,Wang Lianfu³,Lin Zhibin¹,Li Min¹,Yang Baoxue¹⁴

Affiliation:

1. State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China

2. Department of Anatomy, and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, 400016, China

3. JUNCAO Technology Research Institute, Fujian Agriculture and Forestry University, Fuzhou 350002, China

4. Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, 100191, China

Abstract

Ganoderic acid, isolated from Ganoderma lucidum, significantly ameliorated 5-FU induced cognitive impairment via preventing mitochondrial impairment and enhancing neuronal survival and growth.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO03055H

Reference75 articles.

1. Cancer treatment and survivorship statistics, 2019

2. Prevalence, mechanisms, and management of cancer-related cognitive impairment