The trading of space for time under weakly activated catalysis: expeditious synthesis of β-NH2 alcohols via a direct ammonolysis of epoxides with ammonia

Author:

Ma Guolan1,Xu Chang2,Yang Shaoxiong1,Zhu Yanren1,Ye Silei1ORCID,Qin Rui1,Zeng Chongchong1,Du Wenqiang1,Zhang Hongbin1ORCID,Chen Jingbo1ORCID

Affiliation:

1. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Provincial Center for Research & Development of Natural Products, School of Chemical Science and Technology, Yunnan University, Kunming, 650500, P. R. China

2. School of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, 650500, P. R. China

Abstract

The direct synthesis of β-NH2 alcohols via flexible ammonolysis of epoxides is still a challenging and unresolved problem.

Funder

National Natural Science Foundation of China

Yunnan Provincial Science and Technology Department

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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