The protective effects of beta-mangostin against sodium iodate-induced retinal ROS-mediated apoptosis through MEK/ERK and p53 signaling pathways-Reference-Cited by-全球学者库

The protective effects of beta-mangostin against sodium iodate-induced retinal ROS-mediated apoptosis through MEK/ERK and p53 signaling pathways

Published:2023 Issue:24 Volume:14 Page:10896-10909
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Chang Yuan-Yen¹^ORCID,Wang Meilin¹,Yeh Jui-Hsuan²,Tsou Shang-Chun³,Chen Tzu-Chun²,Hsu Min-Yen⁴,Lee Yi-Ju⁵,Wang Inga⁶,Lin Hui-Wen⁷^ORCID

Affiliation:

1. Department of Microbiology and Immunology, School of Medicine, Chung Shan Medical University and Clinical Laboratory, Chung Shan Medical University Hospital, Taichung 40201, Taiwan

2. Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan

3. Department of Nutrition, Chung Shan Medical University, Taichung 40201, Taiwan

4. School of Medicine, Chung Shan Medical University and Department of Ophthalmology, Chung Shan Medical University Hospital, Taichung 40201, Taiwan

5. Department of Pathology, Chung Shan Medical University, Chung Shan Medical University Hospital, Taichung 40201, Taiwan

6. Rehabilitation Sciences & Technology, University of Wisconsin-Milwaukee, Milwaukee, WI, USA

7. Department of Optometry, Asia University, Taichung 41354, Taiwan

Abstract

Previous studies have indicated that NaIO3 induces intracellular reactive oxygen species (ROS) production and has been used as a model for age-related macular degeneration (AMD) due to the selective retinal pigment epithelium (RPE) cell damage it induces.

Funder

Ministry of Science and Technology, Taiwan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO03568A

Reference47 articles.

1. Oxidative stress: The core pathogenesis and mechanism of Alzheimer’s disease

2. Ferroptosis in Parkinson's disease: Molecular mechanisms and therapeutic potential

3. Protective Effect of Quercetin on Sodium Iodate-Induced Retinal Apoptosis through the Reactive Oxygen Species-Mediated Mitochondrion-Dependent Pathway

4. Quercetin Alleviates the Accumulation of Superoxide in Sodium Iodate-Induced Retinal Autophagy by Regulating Mitochondrial Reactive Oxygen Species Homeostasis through Enhanced Deacetyl-SOD2 via the Nrf2-PGC-1α-Sirt1 Pathway

5. The Protective Effects of α-Mangostin Attenuate Sodium Iodate-Induced Cytotoxicity and Oxidative Injury via Mediating SIRT-3 Inactivation via the PI3K/AKT/PGC-1α Pathway