Rational construction of polycystine-based nanoparticles for biomedical applications

Author:

Chen Jinjin1ORCID,Yang Jiazhen23,Ding Jianxun23ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107 Yanjiang West Road, Guangzhou 510120, P. R. China

2. Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, China

3. School of Applied Chemistry and Engineering, University of Science and Technology of China, 96 Jinzhai Road, Hefei 230026, P. R. China

Abstract

This review summarizes the development of reduction-responsive disulfide-crosslinked PCys2-based nanoparticles through one-pot polymerization, post-polymerization modification, and post-polymerization self-assembly for biomedical applications.

Funder

Guangdong Science and Technology Department

Youth Innovation Promotion Association of the Chinese Academy of Sciences

National Natural Science Foundation of China

Jilin Scientific and Technological Development Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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