Iodine-catalyzed regioselective direct sulfenylation of uracil with sulfonyl hydrazide as sulfur source under solvent free conditions-Reference-Cited by-同舟云学术

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Iodine-catalyzed regioselective direct sulfenylation of uracil with sulfonyl hydrazide as sulfur source under solvent free conditions

Published:2024 Issue:7 Volume:14 Page:4587-4590
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wang Cong¹²,Peng Qi-Yun¹^ORCID,Wu Yi¹,He Yan-Ling³,Zheng Xiao-He³,Wang Hai-Bo⁴,Xin Jia-Min²,He Qing¹,Xie Jun¹,Tang Lei¹⁵

Affiliation:

1. School of Pharmacy, Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, China

2. The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Formulation (R&D) Department, Guiyang 550001, China

3. Zhejiang Hisun Pharmaceutical Co., Ltd., Taizhou, Zhejiang 318000, China

4. Zhejiang Hongyuan Pharmaceutical Co., Ltd., Linhai, Zhejiang 317016, China

5. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medcial University, Guiyang, China

Abstract

A facile method was developed for the selective thioetherification of uracils using sulfonyl hydrazide as the thioetherification reagent.

Funder

National Natural Science Foundation of China

Guizhou Provincial Science and Technology Department

Department of Education of Guizhou Province

Natural Science Foundation of Guizhou Province

Guizhou Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA07398J

Reference23 articles.

1. An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation

2. Therapeutic potential of uracil and its derivatives in countering pathogenic and physiological disorders

3. Identification of 2,4-dihydroxy-5-pyrimidinyl imidothiocarbomate as a novel inhibitor to Y box binding protein-1 (YB-1) and its therapeutic actions against breast cancer

4. Inhibition of nucleoside phosphorylase cleavage of 5-fluoro-2'-deoxyuridine by 2,4- pyrimidinedione derivatives

5. 5-(Phenylthio)acyclouridine: a powerful enhancer of oral uridine bioavailability: relevance to chemotherapy with 5-fluorouracil and other uridine rescue regimens

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