Conductive gradient hydrogels allow spatial control of adult stem cell fate-Reference-Cited by-同舟云学术

Conductive gradient hydrogels allow spatial control of adult stem cell fate

Published:2024 Issue: Volume: Page:
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Song Shang¹²³,McConnell Kelly W.¹^ORCID,Shan Dingying¹,Chen Cheng⁴,Oh Byeongtaek¹,Sun Jindi²,Poon Ada S. Y.⁴,George Paul M.¹⁵^ORCID

Affiliation:

1. Department of Neurology and Neurological Sciences, Stanford University, School of Medicine, 300 Pasteur Dr, MC5778 Stanford Stroke Center, Stanford, CA 94305-5778, USA

2. Department of Biomedical Engineering, The University of Arizona, Tucson, AZ, USA

3. Departments of Neuroscience GIDP, Materials Science and Engineering, BIO5 Institute, The University of Arizona, Tucson, AZ, USA

4. Department of Electrical Engineering, Stanford University, Stanford, CA, USA

5. Stanford Stroke Center and Stanford University School of Medicine, Stanford, CA, USA

Abstract

Conductive gradient hydrogels (CGGs) allow preferential differentiation of human mesenchymal stem cells (hMSCs) toward oligodendrocyte lineage in the center while neuronal lineage at the edge of the scaffold under electrical stimulation.

Funder

National Institutes of Health

Alliance for Regenerative Rehabilitation Research and Training

University of Arizona

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2024/TB/D3TB02269B

Reference52 articles.

1. Physical Cues of Biomaterials Guide Stem Cell Differentiation Fate

2. Recent progress in stem cell differentiation directed by material and mechanical cues

3. Controlling properties of human neural progenitor cells using 2D and 3D conductive polymer scaffolds