Visible-light-induced tandem ring opening/1,6-conjugate addition of cyclobutanols with p-quinone methides under metal- and additive-free conditions

Author:

Zhou Tongyao1,Zeng Jie1,Liu Yang1,Chen Hang1,Wang Haifeng1,Yan Qiongjiao1,Wang Wei1ORCID,Chen Fener123ORCID

Affiliation:

1. Pharmaceutical Research Institute, Wuhan Institute of Technology, Wuhan 430205, P. R. China

2. Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, P. R. China

3. Shanghai Engineering Center of Industrial Catalysis for Chiral Drugs, Shanghai 200433, P. R. China

Abstract

A visible-light-mediated tandem ring opening/1,6-conjugate addition of cyclobutanols with p-quinone methides was developed. This protocol allowed the formation of δ,δ-diaryl ketones in the presence of a readily available organic photocatalyst.

Funder

National Natural Science Foundation of China

Department of Education of Hebei Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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