Engineering Yarrowia lipolytica for sustainable production of the chamomile sesquiterpene (−)-α-bisabolol-Reference-Cited by-同舟云学术

Engineering Yarrowia lipolytica for sustainable production of the chamomile sesquiterpene (−)-α-bisabolol

Published:2021 Issue:2 Volume:23 Page:780-787
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Ma Yirong¹²³⁴,Li Wenjuan¹²³⁴,Mai Jie¹²³⁴,Wang Jinpeng¹²³⁴,Wei Yongjun⁵⁶⁷⁸⁹^ORCID,Ledesma-Amaro Rodrigo¹⁰¹¹¹²¹³,Ji Xiao-Jun¹²³⁴⁵^ORCID

Affiliation:

1. College of Biotechnology and Pharmaceutical Engineering

2. Nanjing Tech University

3. Nanjing 211816

4. People's Republic of China

5. Key Laboratory of Advanced Drug Preparation Technologies

6. Ministry of Education

7. School of Pharmaceutical Sciences

8. Zhengzhou University

9. Zhengzhou 450001

10. Department of Bioengineering and Imperial College Centre for Synthetic Biology

11. Imperial College London

12. London SW7 2AZ

13. UK

Abstract

The oleaginous yeast Yarrowia lipolytica was metabolically engineered to produce the chamomile sesquiterpene (−)-α-bisabolol in a green and sustainable way.

Funder

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China

National Key Research and Development Program of China

National Natural Science Foundation of China

Six Talent Peaks Project in Jiangsu Province

Biotechnology and Biological Sciences Research Council

British Council

Newton Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/GC/D0GC03180A

Reference37 articles.

1. New frontiers: harnessing pivotal advances in microbial engineering for the biosynthesis of plant-derived terpenoids

2. Engineering yeast metabolism for production of terpenoids for use as perfume ingredients, pharmaceuticals and biofuels

3. Valuable chemicals by the enzymatic modification of molecules of natural origin: Terpenoids, steroids, phenolics and related compounds

4. Fermentative production and direct extraction of (−)-α-bisabolol in metabolically engineered Escherichia coli

5. Pharmakologische Untersuchungen von Kamillen–Inhaltsstoffen – I. Zur Pharmakologie des (–)–α–Bisabolols und der Bisabololoxide (Übersicht)

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