Synthesis of cyclopenta[<i>b</i>]benzofurans <i>via</i> biomimetic oxidative phenol–enamine [3 + 2] cycloaddition-Reference-Cited by-同舟云学术

Synthesis of cyclopenta[b]benzofurans via biomimetic oxidative phenol–enamine [3 + 2] cycloaddition

Published:2023 Issue:5 Volume:10 Page:1213-1218
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Bashir Muhammad Adnan¹²^ORCID,Chen Xuanjie¹²,Wang Tie¹²,Guo Hui³^ORCID,Zhai Hongbin¹⁴²^ORCID

Affiliation:

1. The State Key Laboratory of Chemical Oncogenomics, Guangdong Provincial Key Laboratory of Nano-Micro Materials Research, School of Chemical Biology and Biotechnology, Shenzhen Graduate School of Peking University, Shenzhen 518055, China

2. Institute of Marine Biomedicine, Shenzhen Polytechnic, Shenzhen 518055, China

3. Tsinghua-Berkeley Shenzhen Institute and The Institute of Biopharmaceutical and Health Engineering Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, People's Republic of China

4. Shenzhen Bay Laboratory, Shenzhen 518055, China

Abstract

A hemin/t-BuOOH-catalyzed oxidative phenol–enamine formal [3 + 2] cycloaddition has been developed, enabling the environmentally benign synthesis of valuable cyclopenta[b]benzofuran scaffolds under sustainable reaction conditions.

Funder

Shenzhen Bay Laboratory

National Natural Science Foundation of China

Shenzhen-Hong Kong Institute of Brain Science

National Ten Thousand Talent Program

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D2QO01916G

Reference50 articles.