Metal-free bioorthogonal click chemistry in cancer theranostics

Author:

Wu Dan1,Yang Kuikun2,Zhang Zhankui1,Feng Yunxuan3,Rao Lang4,Chen Xiaoyuan5ORCID,Yu Guocan3ORCID

Affiliation:

1. College of Materials Science and Engineering, Zhejiang University of Technology Hangzhou, 310014, P. R. China

2. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade, Taipa, Macau 999078, P. R. China

3. Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China

4. Institute of Biomedical Health Technology and Engineering, Shenzhen Bay Laboratory, Shenzhen 518132, P. R. China

5. Yong Loo Lin School of Medicine and Faculty of Engineering, National University of Singapore, Singapore, 117597, Singapore

Abstract

In this Review, recent progress in cancer theranostics on the basis of metal-free bioorthogonal click chemistry is depicted in detail and future prospects in this emerging field are emphasized.

Funder

Natural Science Foundation of Zhejiang Province

National Natural Science Foundation of China

Shenzhen Bay Laboratory

National University of Singapore

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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