Biochemical characterization of Mycobacterium tuberculosis IMP dehydrogenase: kinetic mechanism, metal activation and evidence of a cooperative system-Reference-Cited by-同舟云学术

Biochemical characterization of Mycobacterium tuberculosis IMP dehydrogenase: kinetic mechanism, metal activation and evidence of a cooperative system

Published:2014 Issue:50 Volume:4 Page:26271-26287
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Rostirolla Diana Carolina¹²³⁴⁵,Milech de Assunção Thiago⁶⁷⁸,Bizarro Cristiano Valim¹²³⁴,Basso Luiz Augusto¹²³⁴⁵,Santos Diogenes Santiago¹²³⁴⁵

Affiliation:

1. Centro de Pesquisas em Biologia Molecular e Funcional (CPBMF)

2. Instituto Nacional de Ciência e Tecnologia em Tuberculose (INCT-TB)

3. Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)

4. Porto Alegre, Brazil

5. Programa de Pós-Graduação em Medicina e Ciências da Saúde

6. Gastroenterology Research Unit

7. Mayo Clinic

8. Rochester, USA

Abstract

Proposed kinetic mechanism for MtIMPDH in the presence of K⁺.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA02142H

Reference98 articles.

1. World Health Organization, 2013, Global tuberculosis control: WHO report 2013, WHO/HTM/TB/2013.11

2. Multidrug-resistant tuberculosis

3. Extensively drug-resistant tuberculosis

4. Review: Managing TB in the 21st century: existing and novel drug therapies

5. Advances in the development of new tuberculosis drugs and treatment regimens

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