Type 3 resistant starch from Canna edulis modulates obesity and obesity-related low-grade systemic inflammation in mice by regulating gut microbiota composition and metabolism

Author:

Wu Jiahui1,Qiu Minyi2,Zhang Chi1,Zhang Caijuan3,Wang Nan1,Zhao Fangyuan1,LV Liqiao1,Li Junling1,Lyu-Bu A. G. A.1,Wang Ting4,Zhao Baosheng4,You Shaowei5,Wu Yuanhua6,Wang Xueyong1ORCID

Affiliation:

1. School of Chinese Meteria Medica, Beijing University of Chinese Medicine, Northeast corner of intersection of Sunshine South Street and Baiyang East Road, Fang-Shan District, Beijing, 102488, China

2. Medicament Department, Peking University People's Hospital, Beijing, 100044, China

3. School of Life Science, Beijing University of Chinese Medicine, Beijing, 102488, China

4. Beijing Research Institute of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China

5. The Second Affiliated Hospital of Guizhou University of traditional Chinese Medicine, Guizhou, 550003, China

6. The First Affiliated Hospital of Guizhou University of traditional Chinese Medicine, Gouzhou, 550001, China

Abstract

The beneficial effects of Ce-RS3 might derive from gut microbiota changes, which might improve obesity and metabolic inflammation by altering host-microbiota interactions with impacts on the metabolome.

Funder

Natural Science Foundation of Beijing Municipality

Science and Technology Program of Guizhou Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Reference73 articles.

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4. Global burden of obesity in 2005 and projections to 2030

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