A highly sensitive nanochannel device for the detection of SUMO1 peptides

Author:

Qin Yue12,Zhang Xiaoyu2ORCID,Song Yanling1,Zhong Bowen2,Liu Lu2,Wang Dongdong2,Zhang Yahui2ORCID,Lu Wenqi2,Zhao Xinjia2ORCID,Jia Zhiqi1,Li Minmin2ORCID,Zhang Lihua2ORCID,Qing Guangyan23ORCID

Affiliation:

1. College of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, No. 11 Street, Economic and Technological Development Zone, Shenyang 110142, P. R. China

2. CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, P. R. China

3. College of Chemistry and Chemical Engineering, Wuhan Textile University, 1 Sunshine Road, Wuhan 430200, P. R. China

Abstract

Current techniques could not accurately identify SUMO1, here we report a cyclic peptide with strong affinity toward SUMO1, the immobilization of CP on the nanochannel constructs a highly sensitive and specific device for detecting SUMO1 peptides.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Dalian Institute of Chemical Physics

Department of Education of Liaoning Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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