Evaluation of osteogenesis and angiogenesis of icariin loaded on micro/nano hybrid structured hydroxyapatite granules as a local drug delivery system for femoral defect repair

Author:

Wu Yuqiong12345,Xia Lunguo67234,Zhou Yuning82395,Ma Wudi82395,Zhang Na101112135,Chang Jiang101112135,Lin Kaili101112135,Xu Yuanjin82395,Jiang Xinquan12345

Affiliation:

1. Department of Prosthodontics

2. Ninth People's Hospital affiliated to Shanghai Jiao Tong University

3. School of Medicine

4. Shanghai 200011

5. China

6. Center of Craniofacial Orthodontics

7. Department of Oral and Maxillofacial Surgery

8. Department of Oral Surgery

9. Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology

10. State Key Laboratory of High Performance Ceramics and Superfine Microstructure

11. Shanghai Institute of Ceramics

12. Chinese Academy of Sciences

13. Shanghai 200050

Abstract

Icariin has been identified to promote osteogenic differentiation of bone mesenchymal stem cells (BMSCs).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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