Insights into the time-course cellular effects triggered by iron oxide nanoparticles by combining proteomics with the traditional pharmacology strategy

Author:

Meng Yuqing1,Liu Yanqing1,Zhu Yongping1,Qiu Chong1,Ma Ang1,Liu Dandan1,Zhang Shujie1,Gu Liwei1ORCID,Zhang Junzhe1ORCID,Wang Jigang12ORCID

Affiliation:

1. State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China

2. Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore

Abstract

This study investigated the time-course cellular effects on the response of RAW 264.7 cells caused by Si-IONPs via pharmacological and mass spectrometry-based proteomics techniques.

Funder

National Natural Science Foundation of China

CAMS Central Public Welfare Scientific Research Institute Basal Research Expenses

China Academy of Chinese Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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