Synthesis, characterization and biological activity of organometallic derivatives of the antimalarial drug mefloquine as new antischistosomal drug candidates-Reference-Cited by-同舟云学术

Synthesis, characterization and biological activity of organometallic derivatives of the antimalarial drug mefloquine as new antischistosomal drug candidates

Published:2018 Issue:11 Volume:9 Page:1905-1909
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

d'Orchymont Faustine¹²³⁴,Hess Jeannine¹²³⁴^ORCID,Panic Gordana⁵⁶⁷⁴⁸^ORCID,Jakubaszek Marta⁹¹⁰¹¹¹²¹³^ORCID,Gemperle Lea¹²³⁴,Keiser Jennifer⁵⁶⁷⁴⁸^ORCID,Gasser Gilles⁹¹⁰¹¹¹²¹³^ORCID

Affiliation:

1. Department of Chemistry

2. University of Zurich

3. CH-8057 Zurich

4. Switzerland

5. Department of Medical Parasitology and Infection Biology

6. Swiss Tropical and Public Health Institute

7. Basel

8. University of Basel

9. Laboratory for Inorganic Chemical Biology

10. Chimie ParisTech

11. PSL University

12. F-75005 Paris

13. France

Abstract

The design, synthesis, characterization and biological evaluation of new ferrocenyl and ruthenocenyl derivatives of the antimalarial mefloquine is described.

Funder

H2020 European Research Council

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Universität Zürich

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00396C

Reference46 articles.