Systematic computational strategies for identifying protein targets and lead discovery

Author:

Kataria Arti1,Srivastava Ankit2,Singh Desh Deepak3ORCID,Haque Shafiul4,Han Ihn5,Yadav Dharmendra Kumar6ORCID

Affiliation:

1. Laboratory of Bacteriology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Hamilton, MT, 59840, USA

2. Laboratory of Neurological Infections and Immunity, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Hamilton, MT, 59840, USA

3. Amity Institute of Biotechnology, Amity University Rajasthan, Jaipur, India

4. Research and Scientific Studies Unit, College of Nursing and Health Sciences, Jazan University, Jazan-45142, Saudi Arabia

5. Plasma Bioscience Research Center, Applied Plasma Medicine Center, Department of Electrical & Biological Physics, Kwangwoon University, Seoul 01897, Republic of Korea

6. Department of Biologics, College of Pharmacy, Gachon University, Hambakmoeiro 191, Yeonsu-gu, Incheon 21924, Republic of Korea

Abstract

Computational algorithms and tools have retrenched the drug discovery and development timeline.

Funder

Ministry of Education – Kingdom of Saudi Arabia

Kyung Hee University

Ministry of Education

Publisher

Royal Society of Chemistry (RSC)

Reference141 articles.

1. The Cell as a Collection of Protein Machines: Preparing the Next Generation of Molecular Biologists

2. A. B. S.Srivastava and J.Shankar , Developments and Diversity of Proteins and Enzymes, in Metabolic Engineering for Bioactive Compounds , ed. V. S. A. Kalia , Springer , Singapore , 2017

3. Chapter 4: Protein Interactions and Disease

4. Small molecules, big targets: drug discovery faces the protein–protein interaction challenge

5. Tissue-based map of the human proteome

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