Metal-free oxidative coupling of aryl acetylene with elemental sulphur and amines: facile access to α-ketothioamides

Author:

Sharma Deepika1,Chatterjee Rana1ORCID,Dhayalan Vasudevan2,Dandela Rambabu1ORCID

Affiliation:

1. Department of Industrial and Engineering Chemistry, Institute of Chemical Technology, Indian Oil Odisha Campus, IIT Kharagpur Extension Centre, Mouza Samantapuri, Bhubaneswar-751013, Odisha, India

2. Department of Chemistry, National Institute of Technology Puducherry, Karaikal-609609, Puducherry, India

Abstract

An efficient and novel method has been developed to access α-ketothioamides from the oxidative coupling reaction of alkynes with elemental sulphur and amines using molecular iodine and DMSO medium.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Reference71 articles.

1. G.Dyker , Handbook of C–H Transformations Applications in Organic Synthesis ; Wiley-VCH , Weinheim , 2005

2. Metal Catalyzed Cross-Coupling Reactions , ed. A. De Meijere and F. Diederich , Wiley-VCH , Weinheim , 2nd edn, 2004

3. Metal-Catalyzed Cross-Coupling Reactions , ed. F. Diederich and P. J. Stang , Wiley-VCH , New York , 1998

4. Silver-Mediated Oxidative C–H/C–H Functionalization: A Strategy To Construct Polysubstituted Furans

5. CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

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