(<i>R</i>)-8-Methylsulfinyloctyl isothiocyanate from <i>Nasturtium officinale</i> inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved-Reference-Cited by-同舟云学术

(R)-8-Methylsulfinyloctyl isothiocyanate from Nasturtium officinale inhibits LPS-induced immunoinflammatory responses in mouse peritoneal macrophages: chemical synthesis and molecular signaling pathways involved

Published:2023 Issue:15 Volume:14 Page:7270-7283
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Alcarranza Manuel¹²^ORCID,Villegas Isabel¹²,Recio Rocío³^ORCID,Muñoz-García Rocío¹²^ORCID,Fernández Inmaculada³^ORCID,Alarcón-de-la-Lastra Catalina¹²

Affiliation:

1. Department of Pharmacology, Faculty of Pharmacy, Universidad de Sevilla, 41012 Sevilla, Spain

2. Instituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), Seville, Spain

3. Departamento de Química Orgánica y Farmacéutica, Facultad de Farmacia, Universidad de Sevilla, 41012 Sevilla, Spain

Abstract

Hirsutin, synthesized in a novel way by the “DAG methodology”, showed antioxidant and anti-inflammatory effects in immune murine cells.

Funder

Consejería de Economía, Conocimiento, Empresas y Universidad, Junta de Andalucía

Ministerio de Ciencia, Innovación y Universidades

Consejería de Transformación Económica, Industria, Conocimiento y Universidades

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO02009F

Reference90 articles.

1. Chemical composition, traditional and professional use in medicine, application in environmental protection, position in food and cosmetics industries, and biotechnological studies of Nasturtium officinale (watercress) – a review

2. Nasturtium officinale reduces oxidative stress and enhances antioxidant capacity in hypercholesterolaemic rats

3. Effect of hydroalcoholic extracts of Nasturtium officinale leaves on lipid profile in high-fat diet rats

4. Clinical Trial of 2-Phenethyl Isothiocyanate as an Inhibitor of Metabolic Activation of a Tobacco-Specific Lung Carcinogen in Cigarette Smokers