Issue 29, 2024
From the journal:

Chemical Communications

A highly sensitive ratiometric fluorescence immunoassay based on bioorthogonal nanozymes†

Xiajian Liu,‡a   Nianhua Wang,‡b   Yixuan Hou,a   He Dong,a   Wenhua Liang,b   Xinchun Li*b  and  Youyong Yuan ORCID logo *ac  

* Corresponding authors

a School of Biomedical Sciences and Engineering, Guangzhou International Campus, South China University of Technology, Guangzhou, P. R. China
E-mail: yuanyy@scut.edu.cn

b Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No 151, Guangzhou, China
E-mail: xinchunli@163.com

c National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, P. R. China

Abstract

We designed a novel ratiometric fluorescence immunoassay based on bioorthogonal nanozymes for carcinoembryonic antigen detection. The analytical performance of our designed immunoassay showed a wide linear range, a low detection limit, good reproducibility, selectivity and stability. Thus, bioorthogonal nanozymes hold great potential applications in clinical diagnoses.

Graphical abstract: A highly sensitive ratiometric fluorescence immunoassay based on bioorthogonal nanozymes

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Article information

DOI
https://doi.org/10.1039/D4CC00731J
Article type
Communication
Submitted
17 Feb 2024
Accepted
11 Mar 2024
First published
12 Mar 2024

Chem. Commun., 2024,60, 3978-3981

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A highly sensitive ratiometric fluorescence immunoassay based on bioorthogonal nanozymes

X. Liu, N. Wang, Y. Hou, H. Dong, W. Liang, X. Li and Y. Yuan, Chem. Commun., 2024, 60, 3978 DOI: 10.1039/D4CC00731J

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