Au3Cu tetrapod nanocrystals: highly efficient and metabolizable multimodality imaging-guided NIR-II photothermal agents

Author:

Wang Zhiyi12345,Ju Yanmin64781,Tong Shiyan12345,Zhang Hongchen12345,Lin Jian9101178,Wang Baodui12138ORCID,Hou Yanglong12345ORCID

Affiliation:

1. Beijing Key Laboratory for Magnetoelectric Materials and Devices

2. Department of Materials Science and Engineering

3. College of Engineering

4. Peking University

5. Beijing Innovation Centre for Engineering Science and Advanced Technology

6. College of Life Science

7. Beijing 100871

8. China

9. Synthetic and Functional Biomolecules Center

10. Department of Chemical Biology

11. College of Chemistry and Molecular Engineering, Peking University

12. State Key Laboratory of Applied Organic Chemistry and Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province and, Lanzhou University

13. Lanzhou

Abstract

Au3Cu tetrapod nanocrystals were synthesized. After surface modification, the obtained monodisperse Au3Cu@PEG-Cy5,FA showed great potential as a fluorescence imaging and MSOT imaging-guided photothermal agent in the NIR-II region, which could be metabolized in vitro after treatment.

Funder

National Natural Science Foundation of China

Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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