HSAF-induced antifungal effects in Candida albicans through ROS-mediated apoptosis-Reference-Cited by-同舟云学术

HSAF-induced antifungal effects in Candida albicans through ROS-mediated apoptosis

Published:2016 Issue:37 Volume:6 Page:30895-30904
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ding Yanjiao¹²³⁴⁵,Li Zhenyu¹²³⁴⁵,Li Yaoyao¹²³⁴⁵,Lu Chunhua¹²³⁴⁵,Wang Haoxin⁶³⁴⁵,Shen Yuemao¹²³⁴⁵,Du Liangcheng⁷⁸⁹¹⁰

Affiliation:

1. Key Laboratory of Chemical Biology (Ministry of Education)

2. School of Pharmaceutical Sciences

3. Shandong University

4. Jinan

5. P. R. China

6. State Key Laboratory of Microbial Technology

7. Department of Chemistry

8. University of Nebraska-Lincoln

9. Lincoln

10. USA

Abstract

HSAF, a potent antifungal agent, induced the apoptosis of Candida albicans through reactive oxygen species production. The binding model of HSAF to β-tubulin was simulated by Amber 12 and shown by PyMoL.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA26092B

Reference39 articles.

1. Fungicidal Drugs Induce a Common Oxidative-Damage Cellular Death Pathway

2. A new, broad-spectrum azole antifungal: posaconazole ? mechanisms of action and resistance, spectrum of activity

3. Echinocandins: A ray of hope in antifungal drug therapy

4. Hibicuslide C-induced cell death in Candida albicans involves apoptosis mechanism

5. Unraveling the Biology of a Fungal Meningitis Pathogen Using Chemical Genetics

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