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Ultrasound-targeted photodynamic and gene dual therapy for effectively inhibiting triple negative breast cancer by cationic porphyrin lipid microbubbles loaded with HIF1α-siRNA

  • Published:2018 Issue:42 Volume:10 Page:19945-19956
  • ISSN:2040-3364
  • Container-title:Nanoscale
  • language:en
  • Short-container-title:Nanoscale

Author:

Sun Sujuan12314,Xu Yunxue56783,Fu Peng910113,Chen Min56783,Sun Suhui910113,Zhao Ranran143,Wang Jinrui910113,Liang Xiaolong910113,Wang Shumin12314ORCID

Affiliation:

1. Ordos Clinical Medical School of Inner Mongolia Medical University

2. Hohhot

3. China

4. Ordos

5. Department of Biomedical Engineering

6. College of Engineering

7. Peking University

8. Beijing 100083

9. Department of Ultrasound

10. Peking University Third Hospital

11. Beijing 100191

Abstract

Enhanced PDT and siRNA transfection effect of siRNA@CpMBs were successfully achieved by in situ conversion of MBs to NPs.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Peking University Third Hospital

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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