Induction of cell cycle arrest and apoptosis by copper complex Cu(SBCM)2 towards oestrogen-receptor positive MCF-7 breast cancer cells-Reference-Cited by-同舟云学术

Induction of cell cycle arrest and apoptosis by copper complex Cu(SBCM)2 towards oestrogen-receptor positive MCF-7 breast cancer cells

Published:2019 Issue:32 Volume:9 Page:18359-18370
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Foo Jhi Biau¹²³⁴⁵^ORCID,Ng Li Shan¹²³,Lim Ji Hui¹²³,Tan Pau Xien¹²³,Lor Yan Zhi¹²³,Loo Jason Siau Ee⁴⁵⁶³^ORCID,Low May Lee⁷⁴⁸⁹³,Chan Lee Chin¹⁰¹¹¹²³,Beh Chaw Yee¹³¹⁴¹²³,Leong Sze Wei¹⁰¹¹¹²³,Saiful Yazan Latifah¹⁵¹⁴¹⁶³¹⁷,Tor Yin Sim¹⁸⁵⁶³,How Chee Wun¹²³

Affiliation:

1. Faculty of Pharmacy

2. MAHSA University

3. Malaysia

4. School of Pharmacy

5. Faculty of Health & Medical Sciences

6. Taylor's University

7. Department of Pharmaceutical Chemistry

8. International Medical University

9. Kuala Lumpur

10. Virology Lab 1

11. Faculty of Biotechnology and Biomolecular Sciences

12. Universiti Putra Malaysia (UPM)

13. Laboratory of Vaccines and Immunotherapeutics

14. Institute of Bioscience

15. Laboratory of Molecular Biomedicine

16. Universiti Putra Malaysia

17. Department of Biomedical Sciences

18. School of Biosciences

Abstract

Cu(SBCM)₂ binds to DNA topoisomerase I, which, in turn, induces cell cycle arrest and apoptosis in MCF-7 breast cancer cells, possibly via p53 signalling pathway.

Funder

Taylor's University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA03130H

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