Trace water in a BF3·OEt2 system: a facile access to sulfinyl alkenylsulfones from alkynes and sodium sulfinates

Author:

Yu Shi-Wei1,Chen Zu-Jia1,Chen Zhao-Hua1,Chen Si-Hong1,Yang Kai2,Xu Wen-Jin1,Wang Zhao-Yang1ORCID

Affiliation:

1. School of Chemistry, South China Normal University; GDMPA Key Laboratory for Process Control and Quality Evaluation of Chiral Pharmaceuticals; Guangzhou Key Laboratory of Analytical Chemistry for Biomedicine; Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, Guangzhou, Guangdong 510006, P. R. China

2. College of pharmacy, Gannan Medical University, Ganzhou 341000, P. R. China

Abstract

An efficient and operationally simple synthesis of β-sulfinyl alkenylsulfones through a BF3·OEt2-promoted reaction of alkynes and sodium sulfinates is developed.

Funder

Basic and Applied Basic Research Foundation of Guangdong Province

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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