A responsive AIE-active fluorescent probe for visualization of acetylcholinesterase activity <i>in vitro</i> and <i>in vivo</i>-Reference-Cited by-同舟云学术

A responsive AIE-active fluorescent probe for visualization of acetylcholinesterase activity in vitro and in vivo

Published:2022 Issue:11 Volume:6 Page:1515-1521
ISSN:2052-1537
Container-title:Materials Chemistry Frontiers
language:en
Short-container-title:Mater. Chem. Front.

Author:

Xiang Chunbai¹,Dirak Musa²^ORCID,Luo Yuan¹,Peng Yonglin³,Cai Lintao¹^ORCID,Gong Ping¹,Zhang Pengfei¹^ORCID,Kolemen Safacan²⁴⁵⁶^ORCID

Affiliation:

1. Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China

2. Department of Chemistry, Koc University, 34450 Istanbul, Turkey

3. Pinete (Zhongshan) Biotechnology Co., Ltd., Digital trade building, No. 6, Xiangxing Road, Torch Development Zone, Zhongshan, 528400, China

4. Surface Science and Technology Center (KUYTAM), Koc University, 34450 Istanbul, Turkey

5. Boron and Advanced Materials Application and Research Center, Koc University, 34450 Istanbul, Turkey

6. TUPRAS Energy Center (KUTEM), Koc University, 34450 Istanbul, Turkey

Abstract

An aggregation-induced emission (AIE) active light up fluorescent probe (TCFPB-AChE) was developed for selective in vitro and in vivo imaging of acetylcholinesterase activity.

Funder

Shenzhen Fundamental Research Program

Bilim Akademisi

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QM/D2QM00239F

Reference53 articles.

1. History and New Developments of Assays for Cholinesterase Activity and Inhibition

2. Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states