In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides-Reference-Cited by-同舟云学术

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In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides

Published:2021 Issue:2 Volume:2 Page:513-522
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Rogers Joseph M.¹²³⁴⁵^ORCID,Nawatha Mickal⁶⁷⁸⁹,Lemma Betsegaw¹⁰¹¹¹²¹³¹⁴,Vamisetti Ganga B.⁶⁷⁸⁹,Livneh Ido¹⁵⁷¹⁶⁹,Barash Uri¹⁵⁷¹⁶⁹,Vlodavsky Israel¹⁵⁷¹⁶⁹,Ciechanover Aaron¹⁵⁷¹⁶⁹,Fushman David¹⁰¹¹¹²¹³¹⁴,Suga Hiroaki¹²³⁴⁵^ORCID,Brik Ashraf⁶⁷⁸⁹^ORCID

Affiliation:

1. Department of Chemistry

2. Graduate School of Science

3. The University of Tokyo

4. Tokyo 113-0033

5. Japan

6. Schulich Faculty of Chemistry

7. Technion-Israel Institute of Technology

8. Haifa 3200008

9. Israel

10. Department of Chemistry and Biochemistry

11. Center for Biomolecular Structure and Organization

12. University of Maryland

13. College Park

14. USA

15. The Rappaport Faculty of Medicine and Research Institute

16. Haifa 31096

Abstract

Cyclic peptides containing unnatural amino acids can modulate Lys-48 ubiquitin chains in cells and animals.

Funder

H2020 European Research Council

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Novo Nordisk Fonden

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CB/D0CB00179A

Reference56 articles.

1. THE UBIQUITIN SYSTEM

2. New insights into ubiquitin E3 ligase mechanism

3. Ubiquitylation Directly Induces Fold Destabilization of Proteins

4. Ubiquitin not only serves as a tag but also assists degradation by inducing protein unfolding

5. The Ubiquitin Code

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1. Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation;Nature Communications;2023-11-08

2. Combining Chemical Protein Synthesis and Random Nonstandard Peptides Integrated Discovery for Modulating Biological Processes;Accounts of Chemical Research;2023-06-13

3. Identification of photocrosslinking peptide ligands by mRNA display;Communications Chemistry;2023-05-31

4. In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease;Nature Chemistry;2023-05-22

5. Utilization of macrocyclic peptides to target protein-protein interactions in cancer;Frontiers in Oncology;2022-11-17

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