Characterisation of Sr<sup>2+</sup> mobility in osteoporotic rat bone marrow by cryo-ToF-SIMS and cryo-OrbiSIMS-Reference-Cited by-同舟云学术

Characterisation of Sr²⁺ mobility in osteoporotic rat bone marrow by cryo-ToF-SIMS and cryo-OrbiSIMS

Published:2022 Issue:18 Volume:147 Page:4141-4157
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Kern Christine¹^ORCID,Jamous Reem²,El Khassawna Thaqif²,Rohnke Marcus¹^ORCID

Affiliation:

1. Institute of Physical Chemistry, Justus Liebig University Giessen, Heinrich-Buff-Ring 17, 35392 Giessen, Germany

2. Experimental Trauma Surgery, Faculty of Medicine, Justus Liebig University Giessen, Aulweg 128, 35392 Giessen, Germany

Abstract

Mass spectrometric imaging approach for ex vivo monitoring of drug transport in bone sections. Cryo-ToF-SIMS depth profiling and high-resolution imaging as well as OrbiSIMS analysis revealed inhomogeneous Sr2+ transport in rat bone marrow.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AN/D2AN00913G

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