System analysis identifies distinct and common functional networks governed by transcription factor ASCL1, in glioma and small cell lung cancer
Author:
Affiliation:
1. Chromatin Biology Laboratory
2. Molecular Biology and Genetics Unit
3. Jawaharlal Nehru Centre for Advanced Scientific Research
4. Bangalore-560064
5. India
Abstract
Systematic functional network analysis of ASCL1 revealed that it regulates mitosis and cell proliferation pathways and has distinct functions in glioma and SCLC.
Funder
Department of Biotechnology , Ministry of Science and Technology
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2017/MB/C6MB00851H
Reference71 articles.
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2. The Basic Helix-Loop-Helix Protein Family: Comparative Genomics and Phylogenetic Analysis
3. Ascl1 Coordinately Regulates Gene Expression and the Chromatin Landscape during Neurogenesis
4. Atlas of Genetics and Cytogenetics in Oncology and Haematology, http://atlasgeneticsoncology.org/Genes/GC_ASCL1, accessed January 2015
5. Proneural genes and the specification of neural cell types
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