Synthesis of 2-trifluoromethylated quinolines from CF3-alkenes-Reference-Cited by-同舟云学术

Synthesis of 2-trifluoromethylated quinolines from CF3-alkenes

Published:2021 Issue:19 Volume:19 Page:4303-4319
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Muzalevskiy Vasiliy M.¹²³⁴^ORCID,Sizova Zoia A.¹²³⁴,Abaev Vladimir T.⁵⁶⁴⁷⁸^ORCID,Nenajdenko Valentine G.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Lomonosov Moscow State University

3. 119899 Moscow

4. Russia

5. North Ossetian State University

6. Vladikavkaz

7. North Caucasus Federal University

8. Stavropol 355009

Abstract

α-CF₃-enamines react with 2-nitrobenzaldehydes to give ortho-nitro-substituted α,β-diaryl-CF₃-enones in up to 88% yield. Reduction of the nitro-group promotes intramolecular cyclization to afford 2-CF₃-3-arylquinolines in up to 99% isolated yield.

Funder

Russian Science Foundation

Lomonosov Moscow State University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00098E

Reference58 articles.

1. Ueber einige Produkte der Steinkohlendestillation

2. Heterocyclic Nitrogen Compounds. Part IIA. Hexacyclic Compounds: Pyridine, Quinoline, and Isoquinoline.

3. Mechanism of formation of benzo[g]quinolones via the Combes reaction

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