An AIE-active theranostic probe for light-up detection of Aβ aggregates and protection of neuronal cells-Reference-Cited by-同舟云学术

An AIE-active theranostic probe for light-up detection of Aβ aggregates and protection of neuronal cells

Published:2019 Issue:15 Volume:7 Page:2434-2441
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Yang Yaqi¹²³⁴⁵,Li Shiwu⁶⁷⁸⁹¹⁰,Zhang Qin¹²³⁴⁵,Kuang Ying¹²³⁴⁵,Qin Anjun⁶⁷⁸⁹¹⁰^ORCID,Gao Meng¹¹⁹¹⁰¹²^ORCID,Li Feng¹²³⁴⁵,Tang Ben Zhong⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Brain Function and Disease

2. Department of Neurobiology and Anatomy

3. Zhongshan School of Medicine

4. Sun Yat-sen University

5. Guangzhou 510080

6. State Key Laboratory of Luminescent Materials and Devices

7. Center for Aggregation-Induced Emission

8. Guangzhou International Campus

9. South China University of Technology

10. Guangzhou

11. National Engineering Research Center for Tissue Restoration and Reconstruction

12. China

Abstract

An AIE-active probe of Cur-N-BF₂ is developed for light-up detection of Aβ fibrils and plaques, inhibition of Aβ fibrillation, disassembly of preformed Aβ fibrils, and protection of neuronal cells.

Funder

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Pearl River S and T Nova Program of Guangzhou

Innovation and Technology Commission

Guangdong Province Introduction of Innovative R&D Team

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2019/TB/C9TB00121B

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