Harnessing α-l-fucosidase for in vivo cellular senescence imaging-Reference-Cited by-同舟云学术

Harnessing α-l-fucosidase for in vivo cellular senescence imaging

Published:2021 Issue:29 Volume:12 Page:10054-10062
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Koo Seyoung¹²³⁴^ORCID,Won Miae¹²³⁴^ORCID,Li Hao¹⁵⁶⁴,Kim Won Young¹²³⁴,Li Mingle¹²³⁴^ORCID,Yan Chenxu⁷⁸⁹¹⁰^ORCID,Sharma Amit¹¹¹²¹³^ORCID,Guo Zhiqian⁷⁸⁹¹⁰^ORCID,Zhu Wei-Hong⁷⁸⁹¹⁰^ORCID,Sessler Jonathan L.¹¹⁴¹⁵¹⁶^ORCID,Lee Jin Yong¹⁵⁶⁴^ORCID,Kim Jong Seung¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Korea University

3. Seoul 02841

4. Korea

5. Sungkyunkwan University

6. Suwon 16419

7. Institute of Fine Chemicals

8. East China University of Science and Technology

9. Shanghai 200237

10. China

11. CSIR-Central Scientific Instruments Organisation

12. Chandigarh 160030

13. India

14. University of Texas at Austin

15. Austin

16. USA

Abstract

Evidence of close association of α-fuc with senescence induction highlights the potential of α-fuc as a novel biomarker for cellular senescence. Here, an α-fuc-responsive AIE probe (QM-NHαfuc) allows for the identification of senescent cell in vivo.

Funder

National Research Foundation of Korea

Welch Foundation

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC02259H

Reference48 articles.

1. Four faces of cellular senescence