Exploring cyclin-dependent kinase inhibitors: a comprehensive study in search of CDK-6 inhibitors using a pharmacophore modelling and dynamics approach-Reference-Cited by-同舟云学术

Exploring cyclin-dependent kinase inhibitors: a comprehensive study in search of CDK-6 inhibitors using a pharmacophore modelling and dynamics approach

Published:2023 Issue:48 Volume:13 Page:33770-33785
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Chagaleti Bharath Kumar¹,Saravanan Venkatesan¹,Vellapandian Chitra²,Kathiravan Muthu K.¹³^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur-603203, India

2. Department of Pharmacology, SRM College of Pharmacy, SRMIST, Kattankulathur, Chennai, Tamil Nadu – 603 203, India

3. Dr A. P. J. Abdul Kalam Research Lab, Department of Pharmaceutical Chemistry, SRM College of Pharmacy, SRMIST, Kattankulathur, Chennai, Tamil Nadu – 603 203, India

Abstract

Design and development of novel CDK-6 inhibitors by computational investigation using a ligand based pharmacophore model, ADMET studies, molecular docking and dynamics.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA05672D

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