Efficient synthesis of ynones from carboxylic acids and terminal alkynes via Pd/Cu catalysis using 2-chloroimidazolium chloride as the activation reagent

Author:

Zheng Weixiang123ORCID,Liang Nengde1ORCID,Fu Yi1,Zhong Jing1,Zhang Yan1,Wang Li1,Wang Yuanhua4ORCID,Wang Qiwei135

Affiliation:

1. Department of Chemistry, Xihua University, Chengdu, 610039, China

2. Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041, China

3. University of Chinese Academy of Sciences, Beijing, 100049, China

4. College of Chemistry, Sichuan University, Chengdu, 610041, China

5. Asymmetric Synthesis and Chiral Technology Key Laboratory of Sichuan Province, Research and Application of Small Organic Chiral Molecules Key Laboratory of Yibin City, Department of Chemistry, Xihua University, Chengdu, China

Abstract

Pd/Cu-catalyzed ynone synthesis uses IPrCl-Cl as an activation reagent, enabling reaction between carboxylic acids & terminal alkynes.

Funder

Xihua University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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