Metal complexes as a promising source for new antibiotics-Reference-Cited by-同舟云学术

Metal complexes as a promising source for new antibiotics

Published:2020 Issue:10 Volume:11 Page:2627-2639
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Frei Angelo¹²³⁴⁵^ORCID,Zuegg Johannes¹²³⁴⁵^ORCID,Elliott Alysha G.¹²³⁴⁵^ORCID,Baker Murray⁶⁷⁸⁵^ORCID,Braese Stefan⁹¹⁰¹¹¹²¹³^ORCID,Brown Christopher¹⁴¹⁵⁵,Chen Feng¹⁶¹⁷¹⁸¹⁹^ORCID,G. Dowson Christopher²⁰²¹¹⁷¹⁸¹⁹^ORCID,Dujardin Gilles²²²³²⁴²⁵^ORCID,Jung Nicole⁹¹⁰¹¹¹²¹³,King A. Paden²⁶²⁷²⁸²⁹,Mansour Ahmed M.³⁰³¹³²³³^ORCID,Massi Massimiliano³⁴³⁵⁵^ORCID,Moat John²⁰²¹¹⁷¹⁸¹⁹,Mohamed Heba A.³⁶³⁷³⁸¹⁹,Renfrew Anna K.³⁶³⁹⁴⁰⁵^ORCID,Rutledge Peter J.¹⁴¹⁵⁵^ORCID,Sadler Peter J.¹⁶¹⁷¹⁸¹⁹^ORCID,Todd Matthew H.³⁶³⁹⁴⁰⁵⁴¹^ORCID,Willans Charlotte E.³⁶³⁷³⁸¹⁹^ORCID,Wilson Justin J.²⁶²⁷²⁸²⁹^ORCID,Cooper Matthew A.¹²³⁴⁵^ORCID,Blaskovich Mark A. T.¹²³⁴⁵^ORCID

Affiliation:

1. Centre for Superbug Solutions

2. Institute for Molecular Bioscience

3. The University of Queensland

4. St. Lucia

5. Australia

6. School of Molecular Sciences

7. The University of Western Australia

8. 6009 Perth

9. Institute of Organic Chemistry

10. Karlsruhe Institute of Technology (KIT)

11. 76131 Karlsruhe

12. Germany

13. Institute of Biological and Chemical Systems – Functional Molecular Systems (IBCS-FMS)

14. School of Medical Sciences (Discipline of Pharmacology)

15. University of Sydney

16. Department of Chemistry

17. University of Warwick

18. Coventry CV4 7AL

19. UK

20. Antimicrobial Screening Facility

21. School of Life Sciences

22. Institute of Molecules and Matter of Le Mans (IMMM)

23. UMR 6283 CNRS

24. Le Mans Université

25. France

26. Department of Chemistry and Chemical Biology

27. Cornell University

28. Ithaca

29. USA

30. Chemistry Department

31. Faculty of Science

32. Cairo University

33. Egypt

34. School of Molecular and Life Sciences – Curtin Institute for Functional Materials and Interfaces

35. Curtin University

36. School of Chemistry

37. University of Leeds

38. Leeds LS2 9JT

39. The University of Sydney

40. Sydney

41. School of Pharmacy

Abstract

There is a dire need for new compounds to combat antibiotic resistance: metal complexes might provide the solution. 906 metal complexes were evaluated against dangerous ESKAPE pathogens and found to have a higher hit-rate than organic molecules.

Funder

China Scholarship Council

National Health and Medical Research Council

Engineering and Physical Sciences Research Council

National Institute of General Medical Sciences

Helmholtz Association

Swiss National Science Foundation

Deutsche Forschungsgemeinschaft

University of Queensland

Wellcome Trust

Publisher

Royal Society of Chemistry (RSC)