Investigating the hepatoprotective potentiality of marine-derived steroids as promising inhibitors of liver fibrosis-Reference-Cited by-同舟云学术

Investigating the hepatoprotective potentiality of marine-derived steroids as promising inhibitors of liver fibrosis

Published:2023 Issue:39 Volume:13 Page:27477-27490
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Tammam Mohamed A.¹^ORCID,Pereira Florbela²^ORCID,Aly Omnia³,Sebak Mohamed⁴^ORCID,Diab Yasser M.¹,Mahdy Aldoushy⁵,El-Demerdash Amr⁶⁷^ORCID

Affiliation:

1. Department of Biochemistry, Faculty of Agriculture, Fayoum University, Fayoum 63514, Egypt

2. LAQV REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, Universidade Nova de Lisboa, 2829516 Caparica, Portugal

3. Department of Medical Biochemistry, National Research Centre, Cairo 12622, Egypt

4. Microbiology and Immunology Department, Faculty of Pharmacy, Beni-Suef University, Egypt

5. Department of Zoology, Faculty of Science, Al-Azhar University (Assiut Branch), Assiut 71524, Egypt

6. Division of Organic Chemistry, Department of Chemistry, Faculty of Sciences, Mansoura University, Mansoura 35516, Egypt

7. Department of Biochemistry and Metabolism, the John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK

Abstract

The present study investigates multiple interactions of a series of marine steroids with glutathione-S-transferase (GST) and Cu–Zn human superoxide dismutase (Cu–ZnSOD) enzymes, in order to reveal insights into the process of hepatoprotection.

Funder

Mansoura University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA04843H

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