An ALP enzyme-based electrochemical biosensor coated with signal-amplifying BaTiO3 nanoparticles for the detection of an antiviral drug in human blood serum

Author:

Draz Muhammad Umar1,Zia Ul Haq Muhammad1,Hayat Akhtar2ORCID,Ajab Huma3ORCID

Affiliation:

1. Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Pakistan

2. Interdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS University, Islamabad Lahore Campus, Lahore 54000, Pakistan

3. Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, Pakistan

Abstract

The graphical abstract shows the interaction of the TFV drug with the DNA of the affected patient. This study successfully investigated the novel electrochemical-based biosensor for the targeted drug in human blood serum by using an ALP enzyme supported by a modified BaTiO3 nanoparticle electrode.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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