A biocompatible pure organic porous nanocage for enhanced photodynamic therapy

Author:

Zhu Zhong-Hong1ORCID,Zhang Di1,Chen Jian2ORCID,Zou Hua-Hong3ORCID,Ni Zhiqiang1,Yang Yutong1,Hu Yating4ORCID,Liu Ruiyuan2ORCID,Feng Guangxue1ORCID,Tang Ben Zhong5

Affiliation:

1. State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510640, China

2. Guangdong Provincial Key Laboratory of Medical Image Processing, School of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China

3. School of Chemistry and Pharmaceutical Sciences, State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Guangxi Normal University, Guilin 541004, P. R. China

4. Guangzhou Key Laboratory of Low-Dimensional Materials and Energy Storage Devices, School of Materials and Energy, Guangdong University of Technology, Guangzhou 510006, China

5. Shenzhen Institute of Aggregate Science and Engineering, School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen 518172, China

Abstract

A biocompatible porphyrin-based pure organic porous nanocage with large cavity, high porosity as well as enhanced type I and type II reactive oxygen species generation is developed for photodynamic therapy.

Funder

National Natural Science Foundation of China

Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

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