Exploring the mode of action of inhibitors targeting the PhoP response regulator ofSalmonella entericathrough comprehensive pharmacophore approaches

Author:

Tsai Keng-Chang12345,Hung Po-Pin678910,Cheng Ching-Feng118121314,Chen Chinpan1516174ORCID,Tseng Tien-Sheng1889104ORCID

Affiliation:

1. National Research Institute of Chinese Medicine

2. Ministry of Health and Welfare

3. Taipei 112

4. Taiwan

5. The PhD Program in Medical Biotechnology

6. Division of Infectious Disease

7. Department of Internal Medicine

8. Taipei Tzu Chi Hospital

9. The Buddhist Tzu Chi Medical Foundation

10. New Taipei City 231

11. Department of Pediatrics

12. Buddhist Tzu Chi Medical Foundation

13. Taipei and Tzu Chi University

14. Hualien

15. Institute of Biomedical Sciences

16. Academia Sinica

17. Taipei 115

18. Department of Research

Abstract

Comprehensive pharmacophore approaches explore the mode of action of inhibitors targeting PhoP response regulator ofSalmonella enterica.

Funder

Taipei Tzu Chi Hospital

Ministry of Science and Technology, Taiwan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Bacterial envelope stress responses: Essential adaptors and attractive targets;Biochimica et Biophysica Acta (BBA) - Molecular Cell Research;2023-02

2. A natural product from Streptomyces targets PhoP and exerts antivirulence action against Salmonella enterica;Journal of Antimicrobial Chemotherapy;2022-08-16

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