Chemical biology fluorescent tools for <i>in vitro</i> investigation of the multidrug resistant P-glycoprotein (P-gp) expression in tumor cells-Reference-Cited by-同舟云学术

Chemical biology fluorescent tools for in vitro investigation of the multidrug resistant P-glycoprotein (P-gp) expression in tumor cells

Published:2023 Issue:39 Volume:13 Page:27016-27035
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Daumar Pierre¹^ORCID,Goisnard Antoine¹,Dubois Clémence²,Roux Manon²,Depresle Marie²,Penault-Llorca Frédérique³⁴,Bamdad Mahchid¹,Mounetou Emmanuelle¹

Affiliation:

1. Université Clermont Auvergne, Institut Universitaire de Technologie, UMR INSERM-UCA, U1240, Imagerie Moléculaire et Stratégies Théranostiques (IMoST), F-63000 Clermont-Ferrand, France

2. BIOMARQUEURS Company, 5 avenue Blaise Pascal, 63178 Aubière, France

3. Jean Perrin Comprehensive Cancer Center, F-63011 Clermont-Ferrand, France

4. Université Clermont Auvergne, Faculté de Médecine, UMR INSERM-UCA, U1240, Imagerie Moléculaire et Stratégies Théranostiques (IMoST), F-63000 Clermont-Ferrand, France

Abstract

A series of 25 fluorescent conjugates sharing a common peptidic scaffold was developed for in vitro investigation of the multidrug resistant P-glycoprotein (P-gp) expression.

Funder

Région Auvergne-Rhône-Alpes

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA05093A

Reference34 articles.

1. Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System

2. Multidrug transporters: recent insights from cryo-electron microscopy-derived atomic structures and animal models

3. Targeting multidrug resistance in cancer

4. Multidrug resistance in cancer: role of ATP–dependent transporters

5. Three Decades of P-gp Inhibitors: Skimming Through Several Generations and Scaffolds