Hawthorn flavonoid ameliorates cognitive deficit in mice with Alzheimer's disease by increasing the levels of <i>Bifidobacteriales</i> in gut microbiota and docosapentaenoic acid in serum metabolites-Reference-Cited by-同舟云学术

Hawthorn flavonoid ameliorates cognitive deficit in mice with Alzheimer's disease by increasing the levels of Bifidobacteriales in gut microbiota and docosapentaenoic acid in serum metabolites

Published:2022 Issue:23 Volume:13 Page:12371-12382
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zhang Jinxuan¹^ORCID,Hao Junyu¹,Liu Ran¹,Wu Tao¹^ORCID,Liu Rui¹,Sui Wenjie¹,Zhang Min¹²

Affiliation:

1. State Key Laboratory of Food Nutrition and Safety, Food Biotechnology Engineering Research Center of Ministry of Education, Tianjin University of Science &, Technology, Tianjin 300457, China

2. Tianjin Agricultural University, Tianjin 300384, China

Abstract

Hawthorn flavonoid Ameliorates Cognitive Deficit by improving oxidative stress, Aβ accumulation, abnormal activation of microglia, gut microbiota disturbance and serum metabolic disorder in AD mice. It might be considered as a diet supplement to regulate Alzheimer's disease.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO02871A

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