Apoptosis-independent organoruthenium anticancer complexes that overcome multidrug resistance: self-assembly and phenotypic screening strategies-Reference-Cited by-同舟云学术

Apoptosis-independent organoruthenium anticancer complexes that overcome multidrug resistance: self-assembly and phenotypic screening strategies

Published:2017 Issue:5 Volume:8 Page:3641-3649
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Chow Mun Juinn¹²³^ORCID,Alfiean Mohammad⁴⁵⁶,Pastorin Giorgia⁷²³⁸⁶^ORCID,Gaiddon Christian⁹¹⁰¹¹¹²¹³^ORCID,Ang Wee Han¹²³⁸⁶^ORCID

Affiliation:

1. Department of Chemistry

2. National University of Singapore

3. 117543 Singapore

4. School of Chemistry and Life Sciences

5. Nanyang Polytechnic

6. Singapore

7. Department of Pharmacy

8. NUS Graduate School for Integrative Sciences and Engineering

9. Université de Strasbourg

10. Strasbourg

11. France

12. U1113 INSERM

13. Strasbourg 67200

Abstract

Phenotypic screening on a library of combinatorial self-assembled organoruthenium complexes revealed constructs that act on refractory cancers via apoptosis-independent pathways.

Funder

Ministry of Education - Singapore

Ligue Contre le Cancer

Association pour la Recherche sur le Cancer

European Cooperation in Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC00497D

Reference39 articles.

1. Apoptosis and melanoma chemoresistance

2. Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics

3. Apoptosis block as a barrier to effective therapy in non small cell lung cancer

4. DNA Methylation and Apoptosis Resistance in Cancer Cells

5. Death and anti-death: tumour resistance to apoptosis

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