Coating small-diameter ePTFE vascular grafts with tunable poly(diol-co-citrate-co-ascorbate) elastomers to reduce neointimal hyperplasia-Reference-Cited by-同舟云学术

Coating small-diameter ePTFE vascular grafts with tunable poly(diol-co-citrate-co-ascorbate) elastomers to reduce neointimal hyperplasia

Published:2021 Issue:15 Volume:9 Page:5160-5174
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Yu Lu¹²³⁴^ORCID,Newton Emily R.¹²³⁴,Gillis David C.¹²³⁴,Sun Kui¹²³⁴,Cooley Brian C.⁵²³⁴,Keith Andrew N.⁶²³⁴,Sheiko Sergei S.⁶²³⁴,Tsihlis Nick D.¹²³⁴^ORCID,Kibbe Melina R.¹²³⁴⁷^ORCID

Affiliation:

1. Department of Surgery

2. University of North Carolina at Chapel Hill

3. Chapel Hill

4. USA

5. Department of Pathology and Laboratory Medicine

6. Department of Chemistry

7. Department of Biomedical Engineering

Abstract

We report the need to develop POCA elastomers as ascorbate-based surface coating to modify the luminal surface of small-diameter ePTFE grafts in order to overcome graft occlusion induced by neointimal hyperplasia.

Funder

U.S. Department of Veterans Affairs

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00101A

Reference66 articles.

1. Developments in surgical revascularization to achieve improved morbidity and mortality

2. Expanded Polytetrafluoroethylene (ePTFE) Vascular Graft Loses Its Thrombogenicity Six Months after Implantation

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