Development and evaluation of polyacrylamide microspheres loaded with phloretin and tantalum for transcatheter arterial embolization

Author:

Li Liang1ORCID,Wang Mao Qiang12ORCID,Duan Feng2ORCID,Zhang Jin Long3ORCID,Yuan Bing2ORCID,Cui Bao4ORCID,Zhang Heng15ORCID,Yan Jie Yu2ORCID

Affiliation:

1. Chinese PLA Medical School, Beijing 100853, PR China

2. Department of Interventional Radiology, Chinese PLA General Hospital, Beijing 100853, PR China

3. Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, PR China

4. Department of Interventional, Bethune International Peace Hospital, Shijiazhuang, 050082, PR China

5. Department of Radiology, National Clinical Research Center for Geriatric Diseases/Second Medical Center of Chinese PLA General Hospital, Beijing 100853, China

Abstract

SEM results showed that polyacrylamide microspheres (PM) possess a significant porous structure. Following drug loading, the pores were filled with the drug. DSA results show that the X-ray opacity of PMs increases with increasing concentrations of nanosized tantalum powder.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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