Affiliation:
1. Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky; Regional Clinical Hospital
2. Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky
Abstract
Introduction. One of their main aspects in the treatment of patients with bronchial asthma is maintaining adequate control over the course of the disease.The aim: to assess the level of control, the causes of the uncontrolled course of the disease and the quality of life in patients with severe bronchial asthma.Materials and methods. The study involved 160 patients with severe bronchial asthma taking basic anti-inflammatory therapy. The assessment of adherence to baseline therapy was assessed by questionnaires of patients with a modified Morisky-Green questionnaire and a test to assess adherence to inhalers (TAI). A quality of life questionnaire for patients with bronchial asthma (AQLQ) was used to assess quality of life.Results. It was revealed that all patients had reported daily symptoms and a daily need for short acting beta-agonists; 96.6% of the patients enrolled in the study had night awakenings and physical activity restriction. The survey of patients with the help of the Morisky-Green questionnaire showed that deliberate low adherence to therapy was noted in 45.6% of cases, which was formed due to inattention to the hours of medication – 67.1% and missing the drug in good health in 47.9% of patients. Low motivation and low awareness of their disease is recorded in 24.4% of patients.Conclusions. All patients did not achieve control of the disease. In half of patients with severe asthma, there is low deliberate adherence to basic anti-inflammatory therapy, which is formed mainly by missing the drug in good health and inattention to the hours of medication. Asthma symptoms have the greatest impact on the patient’s emotional state, physical activity, and overall quality of life.
Reference37 articles.
1. Demko I.V., Sobko E.A., Chubarova S.V., Solovyeva I.A., Kraposhina A.Yu., Medvedeva N.N. et al. Features of the Systemic Inflammation, External Respiration Functions and Morphological Structure of the Bronchial Mucous Membrane in Severe Bronchial Asthma. Sibirskoye meditsinskoye obozreniye = Siberian Medical Review. 2014;(5):47–52. (In Russ.) Available at: https://smr.krasgmu.ru/journal/1262_47-52.pdf.
2. Sobko E.A., Demko I.V., Kraposhina A.Yu., Egorov S.A., Ischenko O.P., Soloveva I.A., et al. Quality of Life and Adherence to Therapy at Severe Bronchial Asthma. Byulleten fiziologii i patologii dykhaniya = Bulletin Physiology and Pathology of Respiration. 2019;(74):34–39. (In Russ.) https://doi.org/10.36604/1998-5029-2019-74-34-39.
3. Shadchneva N.A., Solomennaya V.S., Feskova K.V. Studying of the Functional Indicators of External Respiration and Quality of Life in Patients with the Combination of Bronchial Asthma and Chronic Obstructive Pulmonary Disease. Krymskiy terapevticheskiy zhurnal = Crimean Therapeutic Journal. 2019;(2):66–70. (In Russ.) Available at: http://crimtj.ru/Journal.files/2019-2/OA-ShadchnevaSolomnnayaFeskovaStudyinFunctioIndicatExternaRespiraQualityL.pdf.
4. Perel’man N.L., Kolosov V.P. Long-Term Change in Health-Related Quality of Life in Patients with Asthma. Pulmonologiya = Russian Pulmonology. 2018;28(6):708–714. (In Russ.) https://doi.org/10.18093/0869-0189-2018-28-6-708-714.
5. Mahay G, Le Brun M, Taillé C. Asthma Exacerbations in Adults: Preventing and Treat. Presse Med. 2019;48(3 Pt 1):303–309. (In French) https://doi.org/10.1016/j.lpm.2018.12.001.
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