Physicians’ knowledge and preferences regarding pharmacotherapy of pregnant women with respiratory tract infections: research PIKAP-Reference-Cited by-同舟云学术

Physicians’ knowledge and preferences regarding pharmacotherapy of pregnant women with respiratory tract infections: research PIKAP

Published:2024-06-05 Issue:9 Volume: Page:184-192
ISSN:2658-5790
Container-title:Meditsinskiy sovet = Medical Council
language:
Short-container-title:Medicinskij sovet

Author:

Bontsevich R. A.¹^ORCID,Ryabchikova A. A.²^ORCID,Balamutova T. I.³^ORCID,Tsygankova O. V.⁴^ORCID,Kompaniets O. G.⁵^ORCID,Ketova G. G.⁶^ORCID,Bogdanova V. O.⁷^ORCID,Batisheva G. A.⁸^ORCID,Nevzorova V. A.⁹^ORCID,Martynenko I. M.⁹^ORCID,Chukhareva N. A.¹⁰^ORCID,Pakhomov S. P.¹¹^ORCID,Maximov M. L.¹²^ORCID

Affiliation:

1. Mari State University; Belgorod State National Research University; Kazan State Medical Academy – branch of the Russian Medical Academy of Continuing Professional Education

2. Belgorod State National Research University

3. LLC Promedica

4. Novosibirsk State Medical University; Research Institute of Internal and Preventive Medicine, Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences

5. Kuban State Medical University

6. South Ural State Medical University

7. Endocrinology Research Centre; Russian Medical Academy of Continuous Professional Education

8. Voronezh State Medical University named after N.N. Burdenko

9. Pacific State Medical University

10. Fomin Women’s Health Clinic

11. Kursk State Medical University

12. Kazan State Medical Academy – branch of the Russian Medical Academy of Continuing Professional Education; Russian Medical Academy of Continuous Professional Education; Pirogov Russian National Research Medical University

Abstract

Introduction. The most common extragenital pathology during pregnancy includes upper and lower respiratory tract infections (URTI and LRTI), which, if left untreated, leading to obstetric and perinatal pathology. It is relevant to conduct pharmacoepidemiological studies assessing the preferences of specialists regarding the treatment of pregnant women and attitudes towards vaccination in real clinical practice.Aim. To analyze approaches to pharmacotherapy of URTI and LRTI in pregnant women, evaluate the compliance of prescribed drugs with current clinical recommendations and treatment standards.Materials and methods. The study was conducted from 2018 to 2022 using an anonymous questionnaire method in seven regions of Russia.Results and discussion. A total of 227 physicians from seven regions of Russia were surveyed, with 66.8% being internal medicine doctors and 33.2% obstetrician-gynecologists. This study revealed that physicians’ knowledge regarding the rational use of antimicrobial drugs (AMD) in pregnant women is insufficient. Respondents showed better results in the use of AMD in the treatment of pneumonia, with 78.7% of surveys indicating correct tactics. The worst results were observed in answering the question about the appropriateness of prescribing AMD for URTI, tracheitis, and bronchitis (40.3% to 67.7% of respondents made incorrect choices). Overall, 57.7% of respondents understand the importance of vaccination among pregnant women.Conclusion. The results of the conducted study indicate that the choice of drugs for the therapy of URTI and LRTI, especially AMD, for outpatient treatment of pregnant women in some situations does not fully correspond to the current clinical recommendations in our country. Moreover, it is particularly concerning that some physicians prescribe drugs that are unsafe for pregnant women or lack the necessary evidence base or indications for use.

Publisher

Remedium, Ltd.

Reference18 articles.

1. Baranov II, Malinovskaya VV, Vyzhlova EN, Semenenko TA. Prevention and treatment of influenza and ARVI in pregnant women. Lechaschi Vrach. 2023;2(26):78–84. (In Russ.) https://doi.org/10.51793/OS.2023.26.2.012.

2. Panova IA, Malyshkina AI, Sotnikova NYu, Chasha TV. Prevention of influenza and acute viral infections in pregnant women and newborns. Infectious Diseases: News, Opinions, Training. 2017;(1):32–38. (In Russ.) Available at: https://connexio.ru/media/customer/dddf9189-a080-4a5e-b876-b1aa5e65acdc/file/Panova-Malyshkina-article-Grippferon-_BHejmJt.pdf.

3. Grohskopf LA, Blanton LH, Ferdinands JM, Chung JR, Broder KR, Talbot HK. Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices – United States, 2023–24 Influenza Season. MMWR Recomm Rep. 2023;72(2):1–25. Available at: https://www.cdc.gov/mmwr/volumes/72/rr/rr7202a1.htm.

4. Influenza in Pregnancy: Prevention and Treatment: ACOG Committee Statement No. 7. Obstet Gynecol. 2024;143(2):e24–e30. https://doi.org/10.1097/AOG.0000000000005479.

5. Schaefer C, Peters P, Miller RK (ed.). Drugs During Pregnancy and Lactation. 3rd ed. Munich: Elsevier GmbH, Urban and Fischer Verlag; 2015. 876 p. Available at: https://rudiapt.files.wordpress.com/2017/11/drugs-during-pregnancy-and-lactation-3rd-ed-2015.pdf.