Diarrhea syndrome: current aspects of differential diagnosis and treatment at the stage of primary health care

Abstract

Diarrhea is one of the most common syndromes  encountered in the practice  of a general  practitioner,  a general  practitioner, a pediatrician at the  stage  of providing  primary health  care, as well as a gastroenterologist, an infectious  disease  specialist and a surgeon  at the  stage  of providing  specialized  medical  care. The first part  of the  review is devoted  to the  differential diagnosis of diarrhea, the main pathological conditions  and nosological  forms in which the development of diarrhea syndrome is possible  in real clinical practice  are considered.The second  part of the review is devoted  to a promising  active method  in gastroenterological practice-enterosorption. The main requirements for modern enterosorbents are met by the domestic enterosorbent based on silica (colloidal silicon dioxide) Polysorb®   MP. Its properties are  considered,  data  of comparative studies  with  other  enterosorbents are  given. The studies demonstrating the efficacy and safety of the use of enterosorbent Polysorb®  MP in the complex therapy of infectious  diarrhea in adult patients and in pediatric practice are presented. Diarrhea is one of the most common gastrointestinal symptoms in the new coronavirus  infection  COVID-19.  A number  of studies  have  noted  the  effectiveness of the  use of colloidal  silicon dioxide (Polysorb® MP) in the complex treatment of adults  and children with COVID-19 and as part of the post-COVID syndrome. The use of Polysorb®   MP helps  to reduce  the viral load in the intestine, reduce  diarrhea  and other  clinical symptoms  of gastrointestinal lesions  in COVID-19.Availability of modern  effective and safe enterosorbent Polysorb®  MP in the arsenal  of a doctor at the stage  of providing primary health  care will optimize  drug therapy in patients with diarrhea  syndrome and other comorbid somatic pathologies.