Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer-Reference-Cited by-同舟云学术

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Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer

Published:2009-02-12 Issue:5 Volume:16 Page:629-634
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Hedman M,Muona K,Hedman A,Kivelä A,Syvänne M,Eränen J,Rantala A,Stjernvall J,Nieminen M S,Hartikainen J,Ylä-Herttuala S

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt20094.pdf

Reference21 articles.

1. Baumgartner I, Pieczek A, Manor O, Blair R, Kearney M, Walsh K et al. Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia. Circulation 1998; 97: 1114–1123.

2. Hedman M, Hartikainen J, Syvänne M, Stjernvall J, Hedman A, Kivelä A et al. Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: Phase II results of the Kuopio Angiogenesis Trial (KAT). Circulation 2003; 107: 2677–2683.

3. Laitinen M, Zachary I, Breier G, Pakkanen T, Häkkinen T, Luoma J et al. VEGF gene transfer reduces intimal thickening via increased production of nitric oxide in carotid arteries. Hum Gene Ther 1997; 8: 1737–1744.

4. Mäkinen K, Manninen H, Hedman M, Matsi P, Mussalo H, Alhava E et al. Increased vascularity detected by digital subtraction angiography after VEGF gene transfer to human lower limb artery: a randomized, placebo-controlled, double-blinded phase II study. Mol Ther 2002; 6: 127–133.

5. Ylä-Herttuala S, Martin JF . Cardiovascular gene therapy. Lancet 2000; 335: 213–222.

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