Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85α-Reference-Cited by-同舟云学术

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Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85α

Published:2000-11 Issue:3 Volume:26 Page:379-382
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Fruman David A.,Mauvais-Jarvis Franck,Pollard Daniel A.,Yballe Claudine M.,Brazil Derek,Bronson Roderick T.,Kahn C. Ronald,Cantley Lewis C.

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng1100_379.pdf

Reference28 articles.

1. Vanhaesebroeck, B. & Waterfield, M.D. Signaling by distinct classes of phosphoinositide 3-kinases. Exp. Cell Res. 253, 239–254 (2000).

2. Fruman, D.A., Meyers, R.E. & Cantley, L.C. Phosphoinositide kinases. Annu. Rev. Biochem. 67, 481–507 (1998).

3. Terauchi, Y. et al. Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 α subunit of phosphoinositide 3-kinase. Nature Genet. 21, 230–235 (1999).

4. Fruman, D.A., Cantley, L.C. & Carpenter, C.L. Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 α gene. Genomics 37, 113–121 (1996).

5. Antonetti, D.A., Algenstaedt, P. & Kahn, C.R. Insulin receptor substrate 1 binds two novel splice variants of the regulatory subunit of phosphatidylinositol 3-kinase in muscle and brain. Mol. Cell. Biol. 16, 2195–2203 (1996).

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